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AKB48 is a pentyl indazole with structural similarity to JWH 018 adamantyl carboxamide and STS-135, which are synthetic cannabinoids (CBs) that may be sold for recreational use. AKB48 N-(5-fluoropentyl) analog differs structurally from AKB48 by having fluorine at the terminal carbon of the pentyl chain. While the physiological properties of this compound are not known, quinolones with adamantyl-carboxamide moieties display high affinity for the peripheral CB2 receptor but greatly reduced affinity for the central CB1 receptor.
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